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How many cases of pediatric multisystem inflammatory syndrome will be reported in the US, UK, EU member states and Japan, by the end of 2020?

Pediatric multisystem inflammatory syndrome is a potentially novel disease in children that is thought to be associated with COVID-19. According to The Royal College of Paediatrics and Child Health, the clinical presentation as currently understood is as follows:

  • Persistent fever, inflammation (neutrophilia, elevated CRP and lymphopaenia) and evidence of single or multi-organ dysfunction (shock, cardiac, respiratory, renal, gastrointestinal or neurological disorder)
  • Exclusion of any other microbial cause
  • SARS-CoV-2 PCR testing may be positive or negative

As of 15 May 2020, 17 U.S. states and 6 European countries are reporting cases. So far, most of the cases that have been identified and studied are in New York, the United Kingdom and Italy.

This disease is rare, poorly understood, and a link to SARS-CoV-2 infection has not yet been conclusively established. Previous studies have suggested that some common cold human coronaviruses are not linked to childhood diseases similar to pediatric multisystem inflammatory syndrome while others do seem to be linked.

This questions asks: How many cases of pediatric multisystem inflammatory syndrome will be reported in the US, UK, EU member states and Japan, by the end of 2020?

This question resolves as the number of reported cases in the US, UK, EU member states, and Japan in 2020 according to medical publications or credible media reports.

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